Why the study?
Does oral clonidine premedication preserve heart rate variability and reduce analgesic requirements in patients undergoing laparoscopic cholecystectomy?
Population
32 patients scheduled for elective laparoscopic cholecystectomy
Comparison
Oral clonidine 150 micro g before anesthesia vs Oral antacid before anesthesia
Design
RCT, randomized, double-blinded
Follow-up
24 hours
Authors
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Supports clonidine premedication to preserve HRV and reduce analgesics in cholecystectomy; extends RCT evidence for perioperative alpha-2 agonists.
Does oral clonidine premedication preserve heart rate variability and reduce analgesic requirements in patients undergoing laparoscopic cholecystectomy?
Oral clonidine premedication preserves heart rate variability and reduces postoperative analgesic requirements in patients undergoing laparoscopic cholecystectomy.
Yu et al. (2003) studied this question.
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