Key result
Catheter-mounted ultrasound transducers create lesions up to 9 mm deep in canine models.
Why the study?
Ultrasound is a potential energy source for cardiac ablation, and small ultrasound applicators required testing for their ability to create cardiac tissue lesions.
Does ultrasound energy delivered via catheter produce adequate lesions in cardiac tissue for potential ablation of arrhythmias?
Does ultrasound energy delivered via catheter produce adequate lesions in cardiac tissue for potential ablation of arrhythmias?
Ultrasound transducers mounted on cardiac catheters can produce lesions of sufficient depth, demonstrating potential utility for intracardiac ablation of arrhythmias.
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Preclinical lesion creation shown in canine tissue; leaves open translation to human arrhythmia ablation.
He et al. (1995) studied Cardiac arrhythmias (n=7). Ultrasound energy was evaluated on Lesion depth. Ultrasound transducers mounted on cardiac catheters produced lesions up to 9 mm deep on the epicardium and 8.7 +/- 2.9 mm in the left ventricle in canine models.
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