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December 23, 2003StrokeOpen Access

Improved Detection of Microbubble Signals Using Power M-Mode Doppler

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Why the study?

Does power motion-mode transcranial Doppler improve the detection of microbubble signals compared to single-gate spectral transcranial Doppler in patients with right-to-left shunt?

Population

36 patients with right-to-left shunt detected with standard transcranial Doppler, mean age 44.4, 50% male…

Comparison

Power motion-mode transcranial Doppler using… vs Single-gate spectral transcranial Doppler using…

Design

Cross-sectional, Blindly assessed for microbubble signals count on either…

Authors

MSMaher SaqqurUniversity of TorontoNDNaeem DeanAlberta Health ServicesMSMarcia SchebelBarrow Neurological Institute

Discussion

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Implication

PMD may enhance microbubble detection in right-to-left shunt assessment; leaves open effects on diagnostic accuracy and management pending prospective studies.

Structured PICO

Does power motion-mode transcranial Doppler improve the detection of microbubble signals compared to single-gate spectral transcranial Doppler in patients with right-to-left shunt?

P
Population
36 patients with right-to-left shunt detected with standard transcranial Doppler, mean age 44.4, 50% male, median time from stroke onset to TCD bubble test 12 days.
I
Intervention
Power motion-mode transcranial Doppler (PMD) using novel criteria for detecting emboli signature
C
Comparator
Single-gate spectral transcranial Doppler (TCD) using international emboli criteria
O
Outcome
Microbubble signals (MBS) countsurrogate

Power motion-mode transcranial Doppler detects significantly more microbubble signals than spectral TCD by identifying emboli in both the anterior and middle cerebral arteries.

Cite This Study

Saqqur et al. (2003) studied this question.

synapsesocial.com/papers/6a8d0a5eb7e5f37e3ddacb1dhttps://doi.org/10.1161/01.str.0000106771.62928.66
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Contrast Transcranial Doppler Ultrasound in the Detection of Right-to-Left Shunts1999 · 102 citations
  2. 2Detection of arterial emboli using Doppler ultrasound in rabbits.1991 · 234 citations
  3. 3Complementarity of Contrast Transcranial Doppler and Contrast Transesophageal Echocardiography for the Detection of Patent Foramen ovale in Stroke Patients2007 · 87 citations
  4. 4Recurrent Cerebrovascular Events Associated with Patent Foramen Ovale, Atrial Septal Aneurysm, or Both2001 · 1,369 citations
  5. 5Clinical relevance of intraoperative embolization detected by transcranial Doppler ultrasonography during carotid endarterectomy: A prospective study of 100 patients1994 · 243 citations