January 1, 1976Clinical Science

Isolation of Renal Membranes that Contain Kallikrein, Angiotensin I-Converting Enzyme (Kininase II) and Angiotensinase in the Rat

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Population

Rat kidney cortex

Design

Preclinical

Authors

PWPatrick E. WardUniversity of North Texas EEErvin G. ErdösGeneral / Preventive / Lipids CGClark GedneyState Street (United States)

Discussion

Member takes

Implication

Supports compartmentalized kinin and renin-angiotensin systems in rat kidney; leaves open translational relevance to human renal disease.

Structured PICO

Population

Rat kidney cortex

Intervention

Isolation of renal membranes (plasma membrane, endoplasmic reticulum, brush border)

Outcome

Localization of kallikrein, angiotensin I-converting enzyme (kininase II), and angiotensinase

The study identifies the specific subcellular localization of kallikrein and angiotensin-converting enzymes in rat kidney cortex, suggesting distinct functional sites for these enzymes in renal tubules.

Cite This Study

Ward et al. (1976) studied this question.

synapsesocial.com/papers/6a8d0ec5b7f339304dcdb915 https://doi.org/10.1042/cs051267s

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Isolation of Renal Membranes that Contain Kallikrein, Angiotensin I-Converting Enzyme (Kininase II) and Angiotensinase in the Rat

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Isolation of Renal Membranes that Contain Kallikrein, Angiotensin I-Converting Enzyme (Kininase II) and Angiotensinase in the Rat

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider