Why the study?
Does the concentration of collagen and initial platelet sensitivity affect the measurement of aspirin-induced inhibition of platelet aggregation in normal subjects?
Population
20 normal subjects (human platelets)
Design
Preclinical
Authors
Loading...
Assay conditions for detecting ASA platelet inhibition must account for collagen concentration and baseline sensitivity; leaves open standardization for human testing.
Does the concentration of collagen and initial platelet sensitivity affect the measurement of aspirin-induced inhibition of platelet aggregation in normal subjects?
The ability to detect aspirin-induced inhibition of platelet aggregation depends on the concentration of collagen used and the baseline sensitivity of the platelets to collagen.
Green et al. (1973) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: