Population
Rabbit portal vein smooth muscle cells
Comparison
External Ca2+, Sr2+, and Ba2+ vs Divalent cation-free solution
Design
Preclinical
Authors
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No immediate clinical implications from rabbit cell data; leaves open extension to human vascular ion channel physiology.
Divalent cations (Ca2+, Sr2+, Ba2+) potentiate noradrenaline-evoked cation currents in rabbit portal vein smooth muscle cells by increasing single channel conductance and altering kinetic behavior.
Aromolaran et al. (1999) studied this question.
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