Population
Rabbit portal vein, femoral artery, and ileum smooth muscle
Design
Preclinical
Authors
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PKC selectively mediates phorbol ester Ca2+ sensitization in animal smooth muscle; leaves open its necessity in G-protein pathways for cardiovascular research.
PKC isoenzymes alpha, beta 1, beta 2, epsilon, and theta mediate phorbol ester-induced Ca2+ sensitization but are not essential for G-protein-coupled Ca2+ sensitization in smooth muscle.
Jensen et al. (1996) studied this question.
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