Key result
During embryonic development of skeletal muscles, a cardiac-type C-protein isoform appears transiently before being replaced by slow and fast skeletal muscle C-proteins.
Population
Developing striated muscle cells in vivo and in vitro
Design
Preclinical
Authors
Loading...
Embryonic cardiac C-protein expression in skeletal muscle extends developmental models; leaves open translational relevance to human myogenesis.
This study demonstrates that the earliest C-protein expressed during striated muscle development shares immunological properties with the adult cardiac-type C-protein.
Kawashima et al. (1986) studied Striated muscle development. Monoclonal antibody (C-315) specific for cardiac-type C-protein was evaluated on Expression of C-protein isoforms in developing striated muscle cells. During embryonic development of skeletal muscles, a cardiac-type C-protein isoform appears transiently before being replaced by slow and fast skeletal muscle C-proteins.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: