Key result
Increasing temperature in rabbit soleus slow-twitch muscle fibres increased isometric tension and stiffness, with the force generation step being an entropy-driven, endothermic reaction.
The force generation step in rabbit soleus slow-twitch muscle fibers is highly temperature-sensitive and represents an entropy-driven, endothermic reaction.
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Findings from rabbit skeletal muscle should not guide cardiac care; extends thermodynamic models of contraction for future cardiac studies.
Masataka Kawai (2001) studied this question. Temperature variation (5-37 degrees C) was evaluated on Cross-bridge kinetics and elementary steps of the cross-bridge cycle. Increasing temperature in rabbit soleus slow-twitch muscle fibres increased isometric tension and stiffness, with the force generation step being an entropy-driven, endothermic reaction.
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