Population
Decerebrate, paralysed and ventilated cats
Comparison
Vagotomy and delayed-inflation tests vs Before vagotomy (vagi intact)
Design
Preclinical
Authors
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Supports pontine respiratory circuitry models in animals; leaves open translation to human vagal-cardiorespiratory interactions.
DL pontine neurones receive both vagal-dependent excitatory inputs and central respiratory drive, suggesting a recurrent inhibitory circuitry in respiratory control models.
Dick et al. (2008) studied this question.
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