Key result
Canine cTnI values obtained from the Biosite, Stratus, and Access analyzers were closely correlated (r = 0.61 to 0.89) but had wide limits of agreement and cannot be directly compared.
Population
23 dogs with cardiac disease and reconstituted purified canine free cTnI diluted with canine plasma
Comparison
Measurement of cardiac troponin I using three… vs Comparison among the three analyzers
Design
Preclinical
Authors
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Cannot interchange canine cTnI values across analyzers in practice; leaves open assay standardization for veterinary research.
Observational (n=23)
Effect estimate: r = 0.61 to 0.89
Canine cTnI values obtained from different commercial analyzers are correlated but cannot be directly compared due to wide limits of agreement.
Adin et al. (2006) conducted an observational in cardiac disease (n=23). Biosite Triage Meter, Dade-Behring Stratus, and Beckman-Coulter Access AccuTnI analyzers was evaluated on Correlation and agreement of canine plasma cTnI concentrations between 3 analyzers (r = 0.61 to 0.89). Canine cTnI values obtained from the Biosite, Stratus, and Access analyzers were closely correlated (r = 0.61 to 0.89) but had wide limits of agreement and cannot be directly compared.
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