Key result
Cardiopulmonary bypass decreased 25-hydroxyvitamin D levels in children with congenital heart disease from 21.3 to 19.0 ng/mL immediately post-surgery (P=0.02).
Why the study?
Does cardiopulmonary bypass reduce the levels of 25-hydroxyvitamin D in children with congenital heart disease?
Observational (n=20)
Does cardiopulmonary bypass reduce the levels of 25-hydroxyvitamin D in children with congenital heart disease?
p-value: p=.02
Cardiopulmonary bypass significantly decreases 25-hydroxyvitamin D levels in children with congenital heart disease, primarily by reducing the free fraction.
No takes yet. Share an insight, caveat, or question.
Should not yet change vitamin D management in pediatric cardiac surgery; leaves open need for supplementation trials.
Zahr et al. (2016) conducted an observational in Congenital heart disease (n=20). Cardiopulmonary bypass vs. Pre-surgery baseline was evaluated on 25-hydroxyvitamin D (25OHD) levels (p=.02). Cardiopulmonary bypass decreased 25-hydroxyvitamin D levels in children with congenital heart disease from 21.3 to 19.0 ng/mL immediately post-surgery (P=0.02).
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