Key result
In 395 patients with acute coronary syndrome, high mean platelet volume was an independent predictor of multivessel coronary artery disease and associated with higher Gensini and Syntax scores.
Why the study?
Is mean platelet volume associated with the severity of coronary atherosclerosis in patients with acute coronary syndromes?
Observational (n=395)
Is mean platelet volume associated with the severity of coronary atherosclerosis in patients with acute coronary syndromes?
High mean platelet volume is independently associated with greater angiographic severity of coronary atherosclerosis in patients presenting with acute coronary syndromes.
Authors
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May mark greater atherosclerosis severity; hypothesis-generating and should not yet change risk stratification or practice in acute coronary syndromes.
Murat et al. (2012) conducted an observational in Acute Coronary Syndromes (n=395). High mean platelet volume (MPV) was evaluated on Severity of CAD (assessed with Gensini and Syntax scores) and multivessel CAD. In 395 patients with acute coronary syndrome, high mean platelet volume was an independent predictor of multivessel coronary artery disease and associated with higher Gensini and Syntax scores.
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