Key result
Acute rapid ventricular pacing significantly decreased cardiac output and peak left ventricular systolic pressure (p<0.001) without changing left ventricular ATP or ADP levels.
Why the study?
Does acute rapid ventricular pacing alter hemodynamics, myocardial blood flow, and energetics in anesthetized dogs?
Does acute rapid ventricular pacing alter hemodynamics, myocardial blood flow, and energetics in anesthetized dogs?
p-value: p=<0.001
Acute rapid ventricular pacing causes hemodynamic deterioration without perturbing myocardial energetics, contrasting with the effects of chronic pacing.
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Acute rapid ventricular pacing impairs hemodynamics without altering myocardial energetics in dogs; hypothesis-generating for acute versus chronic pacing effects.
Simmons et al. (1994) studied Acute rapid ventricular pacing (n=7). Rapid ventricular pacing vs. Sinus rhythm (baseline) was evaluated on Hemodynamics, myocardial blood flow, oxygen consumption, and left ventricular ATP/ADP levels (p=<0.001). Acute rapid ventricular pacing significantly decreased cardiac output and peak left ventricular systolic pressure (p<0.001) without changing left ventricular ATP or ADP levels.
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