Regular Aerobic Exercise Training Improves Endothelium-Dependent Arterial Dilation in Patients With Impaired Fasting Glucose

Vehkavaara et al. (1) demonstrated that impaired endothelium-dependent arterial dilation characterizes patients with impaired fasting glucose (IFG). The purpose of the study was to investigate the effects of exercise training on endothelium-dependent arterial dilation in subjects with IFG using noninvasive measurement of flow-mediated, endothelium-dependent dilation of the brachial artery. The study group included 30 sedentary Chinese Han men with IFG between 48 and 74 years of age, mean age 63 ± 12 years. The diagnosis of IFG fulfilled the diagnostic criteria proposed by the American Diabetes Association. The subjects participated in a 6-month exercise training program. Of them, eight discontinued the study after 1 month of training. Additionally, 30 sedentary healthy men aged 46–76 years, mean age 65 ± 11 years, were selected as control subjects. Subjects with IFG underwent a supervised orientation and thereafter performed …