Why the study?
Does sex affect the endocrine and metabolic response to anaesthesia and surgery with buprenorphine in patients undergoing elective total hip replacement?
Population
20 patients (12 men and 8 women) undergoing elective total hip replacement
Comparison
Male sex vs Female sex
Design
Cohort
Follow-up
postoperatively
Authors
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Sex differences in endocrine responses may exist but should not alter practice; leaves open need for randomized confirmation of clinical impact.
Does sex affect the endocrine and metabolic response to anaesthesia and surgery with buprenorphine in patients undergoing elective total hip replacement?
There are significant sex differences in the endocrine and metabolic stress response (prolactin and cortisol) to surgery and buprenorphine analgesia.
Moore et al. (1981) studied this question.
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