Why the study?
Does total intravenous anesthesia with propofol reduce early postoperative hypoxemia compared to inhalation anesthesia with nitrous oxide and isoflurane in non-obese patients undergoing elective cholecystectomy?
Population
50 consecutive non-obese patients, ages 25-65, ASA I-II, scheduled for elective cholecystectomy
Comparison
Total intravenous anesthesia with propofol vs Inhalation anesthesia with nitrous oxide and…
Design
RCT, randomly
Follow-up
3 nights after operation
Authors
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May support preferring propofol TIVA over inhalation anesthesia to reduce early postoperative hypoxemia; confirms benefit in this RCT of non-obese cholecystectomy patients.
Does total intravenous anesthesia with propofol reduce early postoperative hypoxemia compared to inhalation anesthesia with nitrous oxide and isoflurane in non-obese patients undergoing elective cholecystectomy?
Total intravenous anesthesia with propofol significantly reduces the incidence and degree of early postoperative hypoxemia compared to inhalation anesthesia with nitrous oxide and isoflurane.
Georgiou et al. (1996) studied this question.
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