Why the study?
Does nitrous oxide affect postoperative nausea and alertness in patients undergoing upper abdominal surgery?
Population
50 patients undergoing elective upper abdominal surgery
Comparison
Thiopentone-fentanyl-isoflurane-pancuronium… vs Thiopentone-fentanyl-isoflurane-pancuronium…
Design
RCT, Randomly assigned
Follow-up
20 hours
Authors
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Omitting nitrous oxide may hasten postoperative alertness without raising nausea risk; supports selective use over routine inclusion in upper abdominal surgery anesthesia.
Does nitrous oxide affect postoperative nausea and alertness in patients undergoing upper abdominal surgery?
Omitting nitrous oxide during upper abdominal surgery does not reduce the frequency of postoperative nausea but leads to earlier postoperative alertness despite higher isoflurane requirements.
Ranta et al. (1991) studied this question.
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