Key result
Intraoperative nitrous oxide did not influence recovery after laparoscopic cholecystectomy, with median time to return to work being 8 days in both the nitrous oxide and air groups.
Why the study?
Does nitrous oxide influence recovery in healthy patients undergoing laparoscopic cholecystectomy?
Population
42 otherwise healthy patients undergoing laparoscopic cholecystectomy
Comparison
Isoflurane with 70% nitrous oxide in oxygen and… vs Isoflurane in air/oxygen and fentanyl for…
Design
RCT, randomised, double-blind
Follow-up
until return to work and normal daily activities
Authors
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Nitrous oxide remains viable without recovery concerns in laparoscopic cholecystectomy; confirms no effect on return to work.
RCT (n=42)
Double-blind
Randomized
Does nitrous oxide influence recovery in healthy patients undergoing laparoscopic cholecystectomy?
Absolute Event Rate: 8% vs 8%
The use of nitrous oxide during laparoscopic cholecystectomy does not significantly affect postoperative recovery times or return to normal activities.
Jensen et al. (1993) conducted an RCT in Laparoscopic cholecystectomy (n=42). Nitrous oxide vs. Air/oxygen was evaluated on Time until return to work and normal daily activities (median days). Intraoperative nitrous oxide did not influence recovery after laparoscopic cholecystectomy, with median time to return to work being 8 days in both the nitrous oxide and air groups.
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