Why the study?
Does intravenous infusion of 7.5% hypertonic saline reduce renal vascular resistance in anesthetized dogs?
Does intravenous infusion of 7.5% hypertonic saline reduce renal vascular resistance in anesthetized dogs?
Hypertonic saline reduces renal vascular resistance in dogs by suppressing sympathetic neurotransmission to vascular smooth muscle, independent of vagal reflexes.
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Hypertonic saline effects on renal hemodynamics should not change practice; leaves open mechanistic studies beyond vagal reflexes in animals.
Fujita et al. (1991) studied this question.
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