Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
February 1, 1986British journal of surgery

Role of the splanchnic nerves in endocrine and metabolic response to abdominal surgery

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does intra-operative splanchnic nerve blockade reduce endocrine and metabolic responses in patients undergoing elective gastrectomy?

Population

Patients undergoing elective gastrectomy under general anaesthesia

Comparison

Intra-operative splanchnic nerve blockade vs General anaesthesia alone or epidural analgesia…

Design

Cohort

Follow-up

first postoperative day

Authors

CSC ShirasakaKyushu UniversityHTHideo TsujiNational Institute of GeneticsTAT AsohOita University Hospital

Discussion

Loading...

Member takes

Implication

May blunt stress responses in gastrectomy; hypothesis-generating and requires randomized trials before practice change.

Structured PICO

Does intra-operative splanchnic nerve blockade reduce endocrine and metabolic responses in patients undergoing elective gastrectomy?

P
Population
Patients undergoing elective gastrectomy under general anaesthesia (n=12 in the splanchnic blockade group, comparator group size not specified)
I
Intervention
Intra-operative splanchnic nerve blockade
C
Comparator
General anaesthesia alone or epidural analgesia alone
O
Outcome
Intra-operative increase in plasma cortisol, glucose, free fatty acids (FFA), and urinary adrenaline excretionsurrogate

Intra-operative splanchnic nerve blockade significantly reduces the endocrine and metabolic stress responses during upper abdominal surgery.

Cite This Study

Shirasaka et al. (1986) studied this question.

synapsesocial.com/papers/6a902df9c7b7d4543f89db64https://doi.org/10.1002/bjs.1800730224
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Epidural analgesia improves postoperative nitrogen balance.1978 · 167 citations
  2. 2Effect of Splanchnic Nerve Stimulation on Glucagon and Insulin Output in the Dog1975 · 65 citations
  3. 3Oxygen Uptake, Plasma Catecholamines and Cardiac Output during Neurolept‐Nitrous Oxide and Halothane Anaesthesias1982 · 49 citations
  4. 4Attenuation of adrenocortical response to upper abdominal surgery with epidural blockade1983 · 37 citations
  5. 5The Functional Importance of Sympathetic Nerves to the Liver and Endocrine Pancreas1979 · 49 citations