Key result
Isolated cardiac disproportion in fetuses had a 38% positive predictive value for postnatal coarctation of the aorta, with higher PPV before 26 weeks gestation (85% vs 28%, p<0.001).
Why the study?
Does antenatally detected isolated cardiac disproportion predict postnatal coarctation of the aorta in fetuses?
Population
269 fetuses with isolated cardiac disproportion diagnosed in the four-chamber and/or…
Design
Systematic_review
Follow-up
Postnatal
Authors
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Cautious fetal counseling advised given modest PPV for coarctation; extends evidence on gestational timing for risk stratification.
Systematic Review (n=269)
Yes
Does antenatally detected isolated cardiac disproportion predict postnatal coarctation of the aorta in fetuses?
Isolated cardiac disproportion detected antenatally has a 38% positive predictive value for postnatal coarctation of the aorta, with significantly higher specificity when detected in the second trimester.
Ghi et al. (2017) conducted a systematic review in Isolated cardiac disproportion (n=269). Isolated cardiac disproportion was evaluated on Postnatal confirmation of coarctation of the aorta (CoA). Isolated cardiac disproportion in fetuses had a 38% positive predictive value for postnatal coarctation of the aorta, with higher PPV before 26 weeks gestation (85% vs 28%, p<0.001).
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