Key result
The elk1 gene encodes a slowly activating and deactivating potassium channel and, along with other EAG genes, is expressed in rat sympathetic ganglia.
The identification and characterization of the elk1 potassium channel gene suggests an important functional role for EAG channels in the sympathetic nervous system.
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EAG channels may modulate sympathetic excitability; hypothesis-generating for autonomic cardiovascular regulation.
Shi et al. (1998) studied this question. elk1 gene expression was evaluated on Channel characteristics and gene expression distribution. The elk1 gene encodes a slowly activating and deactivating potassium channel and, along with other EAG genes, is expressed in rat sympathetic ganglia.
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