July 1, 1982AJP Cell Physiology

Contractile properties of bundles of fiber segments from skeletal muscles

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Population

Frog and mammalian skeletal muscles

Comparison

Bundles of skeletal muscle fiber segments vs Bundles of intact skeletal muscle fibers

Design

Preclinical

Authors

JFJohn A. FaulknerUniversity of South Florida DCDennis R. ClaflinUniversity of Michigan KMKevin K. McCullyUniversity of Georgia

Discussion

Member takes

Implication

Fiber segments may reliably estimate Vo in animal skeletal muscle studies; leaves open translation to human cardiac applications.

Structured PICO

Population

Frog and mammalian skeletal muscles

Intervention

Bundles of skeletal muscle fiber segments

Comparator

Bundles of intact skeletal muscle fibers

Outcome

Contractile properties including maximum velocity of shortening (Vo), contraction time (TPT), relaxation time (RT1/2), maximum tetanus tension (Po), rate of tension development (dP/dt), and twitch-to-tetanus ratio (Pt/Po)surrogate

Bundles of skeletal muscle fiber segments can provide valid estimates of contractile properties compared to intact fibers.

Cite This Study

Faulkner et al. (1982) studied this question.

synapsesocial.com/papers/6a9037a3e02ba012352da582 https://doi.org/10.1152/ajpcell.1982.243.1.c66

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Contractile properties of bundles of fiber segments from skeletal muscles

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Contractile properties of bundles of fiber segments from skeletal muscles

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider