What question did this study set out to answer?

To measure the threshold of 60-Hz alternating current required to induce ventricular fibrillation across varying body weights, shock durations, and electrode placements.

November 1, 1973IEEE Transactions on Biomedical Engineering

Threshold 60-Hz Current Required for Ventricular Fibrillation in Subjects of Various Body Weights

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Population

Preclinical models (rabbits, puppies, one monkey, dogs, goats, and ponies) of various body weights

Design

Preclinical

Authors

LGL. A. GeddesElectrophysiology PCP. CablerBaylor College of Medicine AMA. G. MooreCentre Hospitalier de l’Université de Montréal

Discussion

Member takes

Implication

Animal VF thresholds scale with body weight; leaves open translation to human electrical safety standards.

Key Points

To measure the threshold of 60-Hz alternating current required to induce ventricular fibrillation across varying body weights, shock durations, and electrode placements.
Delivered 60-Hz alternating current via surface electrodes to rabbits, puppies, one monkey, dogs, goats, and ponies.
Tested electrical exposure durations under and over 1 second, evaluating different electrode pathways including Leads I, II, and III.
Threshold current for fibrillation was influenced by exposure duration, requiring higher current intensities for durations shorter than 1 s.
For a 5-s exposure, the threshold current varied roughly as the square root of body weight according to I = KW^α, where α is approximately 0.5.
Electrode placement altered thresholds significantly, with Lead III (left forelimb to left hindlimb) requiring the lowest current and Lead I (right to left forelimb) requiring the highest.

Structured PICO

Population

Preclinical models (rabbits, puppies, one monkey, dogs, goats, and ponies) of various body weights

Intervention

60-Hz alternating-current applied to surface electrodes at different sites for varying durations

Outcome

Threshold 60-Hz alternating-current values required to induce ventricular fibrillationsurrogate

The threshold 60-Hz current required to induce ventricular fibrillation is a function of body weight, exposure duration, and electrode location, varying approximately as the square root of body weight for a 5-second exposure.

Cite This Study

Geddes et al. (1973) studied this question.

synapsesocial.com/papers/6a905497fdb099d0d8dd815c https://doi.org/10.1109/tbme.1973.324221

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Threshold 60-Hz Current Required for Ventricular Fibrillation in Subjects of Various Body Weights

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Threshold 60-Hz Current Required for Ventricular Fibrillation in Subjects of Various Body Weights

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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