Key result
Decreasing transthoracic pulse duration greatly increases the current threshold required to induce VF in dogs.
Population
12 pentobarbital anesthetized dogs
Design
Preclinical
Authors
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Supports wide safety margin for short-pulse transthoracic electroventilation in dogs; hypothesis-generating and should not yet change clinical practice.
The current required to induce ventricular fibrillation via transthoracic electroventilation electrodes is significantly higher than that needed for ventilation, especially at shorter pulse durations, suggesting a wide safety margin.
Voorhees et al. (1992) studied Ventricular fibrillation (n=12). Transthoracic electrode stimulation was evaluated on Threshold current for producing ventricular fibrillation. In 12 anesthetized dogs, the current required to produce ventricular fibrillation using transthoracic electrodes increased greatly as the pulse duration was decreased from 10 to 0.1 msec.
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