Inhibition of pestivirus infection in cell culture by envelope proteins E(rns) and E2 of classical swine fever virus: E(rns) and E2 interact with different receptors.

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Population

Porcine and bovine cells in culture

Design

Preclinical

Authors

Discussion

Supports distinct CSFV E(rns) and E2 receptor interactions in vitro; leaves open translation to swine pestivirus control.

Population

Porcine and bovine cells in culture

Intervention

Envelope glycoproteins E(rns) and E2 of classical swine fever virus (CSFV)

Outcome

Inhibition of pestivirus infectionsurrogate

E(rns) and E2 envelope proteins of CSFV interact with different cell surface receptors to inhibit pestivirus infection in vitro.

Hulst et al. (1997) studied this question.

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