December 13, 2018PLoS ONEOpen Access

Relationship of body mass index and waist circumference with clinical outcomes following percutaneous coronary intervention

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Why the study?

Does waist circumference or body mass index predict major adverse cardiac events in patients undergoing percutaneous coronary intervention?

Population

1,421 patients following PCI

Comparison

Four quartile groups of BMI and waist circumference

Design

Prospective cohort study

Follow-up

5 years

Authors

YLYonggu LeeHanyang University UJUram JinAjou University WLWon Moo LeeHanyang University Seoul Hospital

Discussion

Member takes

Implication

WC associated with post-PCI MACE; extends BMI observations but leaves open its added value for risk stratification.

Structured PICO

Does waist circumference or body mass index predict major adverse cardiac events in patients undergoing percutaneous coronary intervention?

Population

1,421 patients undergoing percutaneous coronary intervention (PCI) with drug-eluting stents (DES), mean age 63.5, 66.8% male, based in Republic of Korea. Exclusions: <35 years of age, prior coronary artery bypass surgery, debilitating conditions (advanced malignancies, advanced liver cirrhosis, end-stage renal disease, severe autoimmune diseases, cerebrovascular accidents with major sequelae), and life expectancy <12 months.

Intervention

Waist circumference (WC) and Body Mass Index (BMI) evaluated as continuous variables and in quartiles (Q1-Q4)

Comparator

Comparison among quartiles (Q1 vs Q2 vs Q3 vs Q4) of BMI and WC

Outcome

Major adverse cardiac event (MACE), defined as a composite of cardiac death (CD), nonfatal myocardial infarction (NFMI), and target vessel revascularization (TVR) at median 29 months follow-upcomposite

Waist circumference demonstrates a biphasic, U-shaped association with cardiovascular outcomes after PCI, suggesting mild central obesity may be protective while severe central obesity increases risk, whereas BMI does not show this relationship.

Cite This Study

Lee et al. (2018) studied this question.

synapsesocial.com/papers/6a905d689f954bcfeb909c80 https://doi.org/10.1371/journal.pone.0208817

Topics

Percutaneous coronary intervention Chronic total occlusion PCI

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Relationship of body mass index and waist circumference with clinical outcomes following percutaneous coronary intervention

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Relationship of body mass index and waist circumference with clinical outcomes following percutaneous coronary intervention

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider