Why the study?
Does myocardial infarction increase plasma enzyme activity in dogs and humans?
Does myocardial infarction increase plasma enzyme activity in dogs and humans?
This foundational study demonstrates that plasma enzyme levels rise and peak within 24 hours of myocardial infarction, correlating with myocardial muscle necrosis.
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May inform preclinical MI biomarker research; leaves open translation to modern troponin-guided practice.
Siegel et al. (1956) studied this question.
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