I131-Induced Hypothyroidism in Intractable Angina Pectoris

Article1 August 1958I131-INDUCED HYPOTHYROIDISM IN INTRACTABLE ANGINA PECTORISEDWIN C. ALBRIGHT, M.D., PARRY D. SODER, M.D., CHARLES W. CRUMPTON, M.D.EDWIN C. ALBRIGHT, M.D.Search for more papers by this author, PARRY D. SODER, M.D.Search for more papers by this author, CHARLES W. CRUMPTON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-49-2-271 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONThe beneficial effect of thyroidectomy for intractable angina pectoris was first reported in 1933 by Blumgart.1 Subsequent reports2, 3 confirmed and extended the original observations. The hazard of major surgery in the seriously ill cardiac patient limited the number in whom hypothyroidism could be induced surgically. The introduction of radioiodine provided a simple, safe method for induction of hypothyroidism in these poor-risk patients. Numerous reports on the successful use of I131 in treatment of angina pectoris have appeared since 1950.4-10The purpose of this paper is to present the results of I131therapy of 24 euthyroid patients with severe...Bibliography1. BlumgartLevineBerlin HLSADD: Congestive heart failure and angina pectoris: the therapeutic effect of thyroidectomy on patients without clinical or pathologic evidence of toxicity, Arch. Int. Med. 51: 866, 1933. CrossrefGoogle Scholar2. BlumgartRisemanDavisBerlin HLJEDDD: Therapeutic effect of total ablation of normal thyroid on congestive heart failure and angina pectoris: early results in various types of cardiovascular disease and coincident pathologic states without clinical or pathologic evidence of thyroid toxicity, Arch. Int. Med. 52: 165, 1933. CrossrefGoogle Scholar3. ParsonsPurks WHWK: Total thyroidectomy for heart disease, Ann. Surg. 105: 722, 1937. CrossrefMedlineGoogle Scholar4. BlumgartFreedbergKurland HLASGS: Hypothyroidism produced by radioactive iodine (I131) in treatment of euthyroid patients with angina pectoris and congestive heart failure: early results in various types of cardiovascular diseases and associated pathologic states, Circulation 1: 1105, 1950. CrossrefMedlineGoogle Scholar5. WolferthChamberlainMead CCRHJJ: Radioactive iodine in treatment of angina pectoris, Pennsylvania M. J. 54: 352, 1951. MedlineGoogle Scholar6. BlumgartFreedbergKurland HLASGS: Treatment of incapacitated euthyroid cardiac patients by producing hypothyroidism with radioactive iodine, New England J. Med. 245: 83, 1951. CrossrefMedlineGoogle Scholar7. BlumgartFreedberg HLAS: Heart and thyroid: with particular reference to I131 treatment of heart disease, Lewis A. Conner Memorial Lecture, Circulation 6, 222, 1952. CrossrefMedlineGoogle Scholar8. JaffeRosenfeldPobirsStuppy HLMHFWLJ: Radioiodine in treatment of advanced heart disease: end results in one hundred patients, J. A. M. A. 151: 716, 1953. MedlineGoogle Scholar9. BlumgartFreedbergKurland HLASGS: Treatment of incapacitated euthyroid cardiac patients with radioactive iodine, J. A. M. A. 157: 1, 1955. CrossrefMedlineGoogle Scholar10. JaffeRosenfeldPobirsStuppy HLMHFWLJ: Radioiodine treatment of euthyroid cardiac disease, J. A. M. A. 159: 434, 1955. CrossrefMedlineGoogle Scholar11. Albright EC: Treatment of thyrotoxicosis with radioactive iodine, Wisconsin M. J. 52: 631, 1953. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication September 20, 1957.From the Department of Medicine, University of Wisconsin Medical School, Madison.Requests for reprints should be addressed to Edwin C. Albright, M.D., Associate Professor of Medicine, University of Wisconsin Medical School, Madison, Wisconsin. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byFunktionelle StrahlentherapieFunktionelle StrahlentherapieHypometabolic treatment of heart disease 1 August 1958Volume 49, Issue 2Page: 271-277KeywordsAnginaCardiac surgeryHypothyroidismPalliative careThyroidectomy ePublished: 1 December 2008 Issue Published: 1 August 1958 PDF downloadLoading ...