Why the study?
Does short-term hypertension affect regional blood flow and haemodynamic responses to exercise in dogs?
Population
10 dogs (n=5 with one-kidney, one clip hypertension of 1-week duration, n=5 normotensive controls)
Comparison
Treadmill exercise at two levels vs Normotensive control dogs undergoing the same…
Design
Preclinical
Authors
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Supports preserved exercise hyperemia in short-term hypertensive dogs; leaves open translation to chronic human hypertension.
Does short-term hypertension affect regional blood flow and haemodynamic responses to exercise in dogs?
In a canine model of short-term hypertension, vasodilatation in response to exercise-induced metabolic demands in the myocardium and skeletal muscles is not limited.
Jean-Fran ois Liard (1986) studied this question.
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