Why the study?
How effective is clinical control of anticoagulant therapy in a hospital setting?
Population
100 patients receiving anticoagulant therapy in a single hospital
Design
Cohort
Authors
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Supports hospital anticoagulation monitoring; hypothesis-generating and should not yet change practice.
How effective is clinical control of anticoagulant therapy in a hospital setting?
Defining an effective therapeutic range for prothrombin activity in seconds allows for better assessment of anticoagulant therapy, with 80% of patients in this cohort achieving adequate control.
Sullivan et al. (1965) studied this question.
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