Why the study?
Does chronic low-frequency stimulation alter myosin light chain expression at mRNA and protein levels in rat fast-twitch muscle?
Population
Rat fast-twitch muscle
Design
Preclinical
Authors
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Caution against clinical extrapolation from rat data; leaves open post-transcriptional mechanisms in human myopathies.
Does chronic low-frequency stimulation alter myosin light chain expression at mRNA and protein levels in rat fast-twitch muscle?
Chronic low-frequency stimulation of rat fast-twitch muscle induces transitions in myosin light chain expression at both mRNA and protein levels, with some evidence of post-transcriptional regulation.
Kirschbaum et al. (1989) studied this question.
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