Why the study?
Does gadolinium modulate cardiac Na+ current in rabbit ventricle cells?
Does gadolinium modulate cardiac Na+ current in rabbit ventricle cells?
Gadolinium acts as a potent Na+ current blocker near threshold potential, which likely contributes to its suppression of stretch-induced arrhythmias.
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Gd3+ blocks ventricular INa near threshold in rabbits; hypothesis-generating for stretch-arrhythmia suppression, needs in vivo confirmation.
Li et al. (2001) studied this question.
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