Population
Normal dogs (n = 11)
Comparison
Combined infusion of dobutamine and dopamine to… vs Basal conditions and coronary stenosis/occlusion
Design
Preclinical
Authors
Loading...
No O2 limitation explains energetic shifts in animal high-work states; leaves open translation to human HF or ischemia.
Myocardial high-energy phosphate changes observed at high work states are not due to inadequate oxygen availability to the mitochondria.
Zhang et al. (1999) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: