Why the study?
The ability to rule out or in MACE in patients with suspected acute coronary syndrome at ED presentation would benefit patient care and the health care system.
Does the clinical chemistry score (CCS) improve the detection of major adverse cardiac events compared to hs-cTnI alone in emergency department patients with suspected acute coronary syndrome?
Population
Patients in 2 cohorts with suspected acute coronary syndrome presenting to the ED of 3 hospitals in Hamilton, Ontario
Comparison
Clinical chemistry score vs hs-cTnI alone
Design
Diagnostic accuracy study evaluating 2 cohorts
Follow-up
30 days for both cohorts and 90 days for cohort 2
Authors
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CCS may enhance ED MACE risk stratification over hs-cTnI alone; leaves open impact on outcomes pending prospective trials.
Does the clinical chemistry score (CCS) improve the detection of major adverse cardiac events compared to hs-cTnI alone in emergency department patients with suspected acute coronary syndrome?
The clinical chemistry score (CCS) demonstrates superior sensitivity and specificity compared to hs-cTnI alone for predicting 30-day MACE in emergency department patients with suspected acute coronary syndrome.
Kavsak et al. (2020) studied this question.
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