Why the study?
For patients evaluated for suspected acute coronary syndrome, there is uncertainty whether a single hs-cTnI measurement at emergency department presentation can identify patients at both low and high risk for mortality.
Does the Clinical Chemistry Score improve prediction of all-cause mortality compared to hs-cTnI alone in emergency department patients with suspected acute coronary syndrome?
Population
5974 consecutive adult ED patients with a Clinical Chemistry Score taken at presentation
Comparison
Clinical Chemistry Score vs hs-cTnI assay alone
Design
Cohort study
Follow-up
5-year
Authors
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CCS may better identify low-risk ED patients with suspected ACS than hs-cTnI; leaves open whether it should guide practice without prospective validation.
Does the Clinical Chemistry Score improve prediction of all-cause mortality compared to hs-cTnI alone in emergency department patients with suspected acute coronary syndrome?
The Clinical Chemistry Score better identifies emergency department patients with suspected acute coronary syndrome at low and high risk for mortality compared to using published cutoffs for hs-cTnI alone.
Kavsak et al. (2020) studied this question.
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