Why the study?
Does remodeling or growth contribute more to the increased media:lumen ratio in resistance vessels in hypertension?
Does remodeling or growth contribute more to the increased media:lumen ratio in resistance vessels in hypertension?
The structural changes in resistance vessels in hypertension are primarily due to remodeling rather than growth, challenging the role of growth factors in the etiology of essential hypertension.
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Challenges growth factor emphasis in hypertension etiology; leaves open therapeutic targeting and requires prospective confirmation.
Michael J. Mulvany (1993) studied this question.
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