Why the study?
Does propranolol alone or in combination with other agents affect systolic time intervals in hypertensive men?
Does propranolol alone or in combination with other agents affect systolic time intervals in hypertensive men?
Long-term administration of propranolol prolongs the preejection period, indicating a moderate decrease in left ventricular performance that can be monitored using systolic time intervals.
Authors
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Propranolol alone may modestly impair LV performance in hypertension; supports systolic time intervals for beta-blocker monitoring in trials.
Kyle et al. (1980) studied this question.