September 1, 1994AJP Regulatory Integrative and Comparative Physiology
Nonuniform enhancement of baroreflex sensitivity by atrial natriuretic peptide in conscious rats and dogs
Population
Conscious chronically instrumented dogs and rats
Design
Preclinical
Authors
Discussion
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Implication
ANP baroreflex effects in animals do not inform human care; leaves open translation to clinical baroreflex modulation.
Structured PICO
P
Population
Conscious chronically instrumented dogs and rats
I
Intervention
Atrial natriuretic peptide (ANP)
O
Outcome
Blood pressure (BP)-heart rate (HR) baroreflex sensitivity and curvaturesurrogate
Atrial natriuretic peptide selectively enhances nonarterial baroreflex pathways, with its observed effects depending heavily on the measurement technique employed.
Cite This Study
Woods et al. (1994) studied this question.