Population
Lewis rats injected with porcine cardiac myosin and C3H/He mice inoculated with coxsackievirus B3
Comparison
Induction of giant cell myocarditis or viral… vs Comparison between viral and giant cell…
Design
Preclinical
Authors
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Supports local cytokine activity in pericardial effusion during experimental myocarditis; hypothesis-generating and should not yet inform human practice.
Elevated inflammatory cytokines in pericardial effusion suggest it plays an active role in the progression of giant cell myocarditis.
Nakayama et al. (2000) studied this question.
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