Population
Various strains of rats including Lewis (RT-1), Dahl (RT-1), Fisher (RT-1), Dahl (RT-1), and Brown Norway…
Comparison
Immunization with porcine cardiac myosin vs Immunization with Freund's complete adjuvant alone
Design
Preclinical
Authors
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Genetic background dictates rat strain susceptibility to giant cell myocarditis; leaves open MHC relevance in human disease.
The expression and severity of experimental giant cell myocarditis in rats are strongly influenced by genetic factors, including major histocompatibility complex genes.
Shioji et al. (2000) studied this question.
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