Population
Female rats ovariectomized at age 105 days, male rats orchidectomized at age 50 days, and male rats…
Comparison
Testosterone 2.5 mg/day administered for 21 days vs Untreated controls
Design
Preclinical
Follow-up
21 days
Authors
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Testosterone may stimulate renin in male rats; hypothesis-generating for androgen-RAAS links, should not change practice.
Testosterone administration stimulates the secretion of renin in young male rats without significantly altering plasma aldosterone levels.
Katz et al. (1977) studied this question.
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