Population
Male and female rats, along with subgroups of castrated males, flutamide-treated males, castrated males with…
Comparison
Castration, anti-androgen flutamide treatment… vs Baseline or intact state
Design
Preclinical
Follow-up
7 weeks
Authors
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Should not change clinical practice; hypothesis-generating for androgen effects on inactive renin.
This study demonstrates a sexual dimorphism in rat plasma inactive renin, suggesting that androgens are involved in its regulation.
Johannessen et al. (1990) studied this question.
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