Key result
Immobilization stress in rats and acute bicycle exercise in humans stimulated the release of a lower molecular weight form of active renin (MW 38,000-39,000) into the circulation.
Population
Rats and humans
Design
Preclinical
Authors
Loading...
May suggest stress alters renin isoform release; leaves open any clinical relevance or therapeutic implications.
The study demonstrates that increased renin secretion induced by stress or exercise leads to the release of a lower molecular weight form of active renin in both rats and humans.
Jíndra et al. (1991) studied this question. Immobilization stress (rats) and acute bicycle exercise (humans) was evaluated on Molecular weight of active and inactive renin. Immobilization stress in rats and acute bicycle exercise in humans stimulated the release of a lower molecular weight form of active renin (MW 38,000-39,000) into the circulation.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: