Why the study?
Is the ACE gene insertion/deletion polymorphism associated with coronary artery disease or myocardial infarction in Chinese and Indian men?
Population
691 men in Singapore, comprising 378 patients with angiographically confirmed coronary artery disease and…
Comparison
Presence of the D allele of the… vs Matched healthy controls
Design
Case-control
Authors
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No ACE D allele–CAD/MI link in Chinese or Indian men; leaves open ethnic differences versus Caucasian findings.
Is the ACE gene insertion/deletion polymorphism associated with coronary artery disease or myocardial infarction in Chinese and Indian men?
The ACE gene insertion/deletion polymorphism is not associated with coronary artery disease or myocardial infarction in Chinese and Indian men in Singapore, contrasting with findings in Caucasian populations.
Saha et al. (1996) studied this question.
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