Why the study?
Does the ACE gene D/D polymorphism increase the risk of essential hypertension in adult Asian Indians?
Population
350 adult (30 years and older) Asian Indians (184 males and 166 females) from Calcutta and its suburbs
Comparison
ACE gene insertion/deletion polymorphism vs I/I and I/D genotypes
Design
Cross-sectional
Authors
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Supports ACE D/D as hypertension risk marker in Asian Indians; leaves open causal role and need for prospective validation.
Does the ACE gene D/D polymorphism increase the risk of essential hypertension in adult Asian Indians?
The ACE gene D/D polymorphism is significantly associated with an increased risk of essential hypertension in adult Asian Indians.
Das et al. (2008) studied this question.
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