Why the study?
Does the insertion/deletion polymorphism in the ACE gene affect blood pressure response to physical exercise in healthy males?
Population
n=66 healthy, unrelated males with normal blood pressure
Comparison
Angiotensin-converting-enzyme gene… vs ACE gene insertion homozygotes and heterozygotes
Design
Cross-sectional
Authors
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ACE I/D polymorphism was associated with higher diastolic BP at peak exercise; leaves open whether genotyping informs risk stratification or exercise guidance.
Does the insertion/deletion polymorphism in the ACE gene affect blood pressure response to physical exercise in healthy males?
The ACE gene insertion/deletion polymorphism is associated with significant differences in diastolic blood pressure response during and after physical exercise in healthy males.
Friedl et al. (1996) studied this question.
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