Why the study?
Is the insertion/deletion polymorphism of the ACE gene associated with an increased risk of venous thromboembolism?
Is the insertion/deletion polymorphism of the ACE gene associated with an increased risk of venous thromboembolism?
This meta-analysis found no significant association between the ACE I/D polymorphism and VTE, advising against its inclusion in routine thrombophilia workups.
Authors
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No association between ACE DD genotype and VTE; leaves open other genetic factors but does not support inclusion in thrombophilia panels.
Hsiao et al. (2009) studied this question.