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June 1, 1991Diabetic Medicine

Twenty‐four Hour Blood Pressure and Heart Rate Profiles of Diabetic Patients with Abnormal Cardiovascular Reflexes

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Why the study?

Does a nocturnal rise in blood pressure in diabetic patients with autonomic neuropathy predict cardiovascular or renal events?

Population

24 patients with diabetes and 11 non-diabetic patients with essential hypertension

Comparison

24-hour ambulatory blood pressure and heart rate… vs Diabetic patients with normal cardiovascular…

Design

Cohort

Follow-up

27 months

Authors

CLC. LinigerEnsemble Studio Theatre (United States)LFLuc FavreÉcole Nationale Supérieure de Chimie de MontpellierJAJ.‐Ph. AssalConquer Chiari

Discussion

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Implication

Nocturnal BP rise associated with events in diabetic neuropathy; hypothesis-generating, requires prospective confirmation.

Structured PICO

Does a nocturnal rise in blood pressure in diabetic patients with autonomic neuropathy predict cardiovascular or renal events?

P
Population
24 patients with diabetes (18 with abnormal cardiovascular reflexes, 6 with normal reflexes) and 11 non-diabetic patients with essential hypertension
I
Intervention
24-hour ambulatory blood pressure and heart rate monitoring
C
Comparator
Diabetic patients with normal cardiovascular reflexes and non-diabetic patients with essential hypertension
O
Outcome
Fatal and severe non-fatal cardiovascular or renal events at 27 monthshard clinical

A nocturnal rise in blood pressure in diabetic patients with abnormal cardiovascular reflexes is associated with a poor prognosis for cardiovascular and renal events.

Cite This Study

Liniger et al. (1991) studied this question.

synapsesocial.com/papers/6a913e68be68d22e6965e7cbhttps://doi.org/10.1111/j.1464-5491.1991.tb01625.x

Topics

Hypertension management
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Ambulatory Blood Pressure and Heart Rate in Diabetic Patients: an Assessment of Autonomic Function1989 · 73 citations
  2. 2The Value of Cardiovascular Autonomic Function Tests: 10 Years Experience in Diabetes1985 · 1,444 citations
  3. 3The Natural History of Diabetic Autonomic Neuropathy1980 · 745 citations
  4. 4The Relationship Between Autonomic Neuropathy and Urinary Sodium and Albumin Excretion in Insulin‐Treated Diabetics1986 · 47 citations
  5. 5Unawareness of hypoglycaemia and inadequate hypoglycaemic counterregulation: no causal relation with diabetic autonomic neuropathy.1990 · 109 citations